Application of Low Field Bench Top NMR for Upstream and Downstream Stages of Biomanufacturing Process
Application of Low Field Bench Top NMR for Upstream and Downstream Stages of Biomanufacturing Process
09th November 2023 | 10:00am EDT / 7:00am PDT / 3:00pm BST / 4:00pm CEST | Marina Kirkitadze, Head of Process Support & PAT Platform, Analytical Sciences at Sanofi and Gabriella Gerzon, PhD Candidate, York University, Toronto, Canada |BOOK FREE SEAT FOR THIS WEBINAR
The development of applications using the low field bench NMR equipped with the flow cell will be discussed for selected process steps at upstream and downstream stages. In scope will be metabolite concentration measurement during fermentation, and concentration of residuals and excipients during antigen purification.
Presented by Marina Kirkitadze, Head of Process Support & PAT Platform, Analytical Sciences at Sanofi
Marina Kirkitadze is Head of Process Support and PAT Platform, Analytical Sciences North America, Sanofi. She has 20 years of experience in the vaccine industry. Marina received her PhD in Biological Sciences at the Institute of Protein Research, Russian Academy of Sciences, Pushchino, Russia, and her MBA from the University of Phoenix, AZ, USA. Prior to joining Sanofi, Marina was a postdoctoral fellow at the Department of Chemistry, University of Edinburgh, and then at the Center for Neurological Diseases, Brigham and Women’s Hospital and Harvard Medical School. Marina’s focus is on the development and implementation of PAT solutions for in-line monitoring of media components, protein concentration and conformation, process-related residuals, and protein adsorption. Her contributions went towards the CMC section in eBLA application for Adacel, approvals for the new manufacturing facility and its extension, Pentacel, and to Module 3 CTD of Hexaxim vaccine submission. Marina has published 42 manuscripts.
And Gabriella Gerzon, PhD Candidate, York University, Toronto, Canada
Gabriella Gerzon is currently a PhD student in the Biology Department at York University., Toronto, Canada. Gabriella received her MSc. in Biological Sciences from York University and her studies focused on mechanisms of epigenetic signalling in response to DNA damage. Currently, Gabriella’s research is in collaboration with Sanofi Pasteur Ltd. and focuses on the development of various analytical techniques to implement PAT solutions for bioprocess monitoring.
