New Drying Processes for Biopharmaceuticals



05th May 2020 | 10.00 am EST | Sune Klint Andersen, Principal Scientist at Janssen Pharmaceutical Companies of Johnson & Johnson and Lars Markwort co-founder and CEO of Bioinicia SL |WATCH FOR FREE

New Drying Processes for Biopharmaceuticals
and followed by
Electrohydrodynamic Processing for Drying, Micronization and Encapsulation of Labile Bioactives
I will show how electrohydrodynamic processing, commonly known as electrospinning and electrospraying, is used to simultaneously dry and encapsulate labile bioactives. Bioactives are processed from solution, emulsion or suspension into nano- and micro-structured fibres and particles. The process can be run at room temperature and below and is sufficiently mild, that processing of live microorganisms, i.e. probiotics is possible. As a beneficial side-effect, poorly soluble crystalline active pharmaceutical ingredients (API) can be processed into amorphous solid solutions or dispersions with significantly improved solubility and bioactivity. Finally, I will show how electrohydrodynamic processing offers great flexibility to reformulate API into many different delivery forms, ranging from fibrous nonwovens in transmucosal patches to encapsulated particles for improved oral tablets and injectables.
Presented by Sune Klint Andersen, Principal Scientist at Janssen Pharmaceutical Companies of Johnson & Johnson

Sune Klint Andersen is Principal Scientist for Spray Drying at the Janssen Pharmaceutical Companies of Johnson & Johnson. He has a Ph.D. in Chemical Engineering. He has worked with pharmaceutical spray drying for 17 years within process development for R&D and commercial scale, application of Quality-by-Design and PAT, particle engineering, drying kinetics, aseptic spray drying and advantages and disadvantages of spray vs freeze drying processes. He previously worked at Novo Nordisk for 7 years.
Followed by Lars Markwort, co-founder and CEO of Bioinicia SL

Lars Markwort is co-founder and CEO of Bioinicia SL. He holds a Ph.D. in Chemistry and worked for 20 years in the analytical and process equipment industry, supplying mainly the semiconductor and pharmaceutical industries. At Bioinicia he is guiding the scaling up of electrohydrodynamic processes to industrial production with a focus on drying, micronization and encapsulating of labile bioactives for applications in pharmaceuticals and nutraceuticals.
Sponsored by Bioinicia

Bioinicia is a specialty contract development and manufacturing company dedicated to nano and microstructured materials for applications in pharmaceuticals, nutraceuticals, cosmetics and biomedical devices. Bioinicia also develops and commercializes premium quality electrospinning equipment for laboratory to industrial-scale processing.


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